NASC 210 Exam 3

NASC 210 Exam 3 Liberty University

1. A phenotype is the trait that you see or can observe.
2. A parent who carries a disease gene always shows symptoms of the disease.
3. The law of segregation states that alleles of a gene:
4. Genetic disease based on altered genes results in “loss of function” or “gain of function” which causes the disease and its symptoms. Huntington’s disease is caused by an abnormally long protein which causes symptoms. This would be classified as:
5. Austrian monk Gregor Mendel primarily worked with what kind of organisms to do his genetic work?
6. Which of the following is true about Huntington’s disease.
7. Every phenotype, the trait that you observe, is caused by the combination of two alleles or the genotype, so for example, brown eye color is a phenotype which can be produced by a dominant allele (B) such that the genotype for brown eye color could be Bb or BB.
8. Leber congenital amaurosis and osteogenesis imperfecta are both genetic diseases demonstrating:
9. Genetic disease based on altered genes is caused by either “loss of function” or “gain of function” which causes the disease and its symptoms. Cystic Fibrosis involves a defective anion channel. This would be classified as:
10. Recessive disorders tend to be more severe and produce symptoms earlier than dominant disorders.
11. In autosomal dominant inheritance a trait can appear in either sex because an autosome (non-sex chromosome) carries the gene.
12. A mutated recessive allele can never contribute to disease.
13. A single gene OCA2 on chromosome 15 confers eye color by controlling melanin synthesis. But also a second gene can influence the expression of OCA2.
14. The ABO blood group alleles found in the human population are an example of;
15. The bodies of the Royal Romanovs, the ruling family of Russia in the early 1900s were exhumed in the 1990s and their DNA was sequenced. Geneticists found a variation in the mitochondrial DNA sequence among the royal family members. The variation was explained by the phenomena of:
16. Using and understanding pedigrees are important today because they help families identify the risk of transmitting an inherited disease
17. LDL is the carrier of cholesterol in blood.
18. Mendel crossed some yellow round pea plants with wrinkled green pea plants. The traits of yellow and round were dominant. In the first generation, the F1 generation all the offspring were;
19. In Alzheimer disease which parts of the brain are affected?
20. The Mitochondrial Eve theory is a theory about:
21. Protein tau can form sticky“tangles” as part of the cause of Alzheimer disease.
22. What percent of cases of Alzheimer disease are familial (inherited)?
23. Amyloid plaques are the suspected cause of Alzheimer disease.